Trinity Evolution is an allograft comprised of cancellous bone with viable osteogenic and osteoprogenitor cells retained within the matrix and a demineralized cortical bone component. Trinity Evolution offers an ideal alternative to autograft and other bone grafting options.
Adult mesenchymal stem cells (MSCs) are multipotential and capable of responding to their environment to differentiate into a variety of cells as needed. When implanted in patients, MSCs and osteoprogenitor cells do not stimulate an immune response.1
Trinity Evolution is processed by the Musculoskeletal Transplant Foundation (MTF), a nonprofit organization dedicated to providing quality tissue. Every step, from donor screening to cryopreservation and pre-release testing, has been designed to maximize cell health and ensure patient safety.
Ensuring quality at every step:
Trinity Evolution supplies the three essential components for robust bone formation:
Le Blanc, K, et al. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol, 2003. 31(10): p. 890.6 and Neimeyer, P., et al., Mesenchymal stem cell-based HLA-independent cell therapy for tissue engineering of bone and cartilage. Curr Stem Cell Res Ther, 2006. 1(1): p. 21-7.
Data on file with MTF
Trinity Evolution is an allograft intended for the treatment of musculoskeletal defects.
Trinity Evolution Brochure
Trinity Evolution Patient Brochure
Musculoskeletal Transplant Foundation (MTF)
Trinity Evolution IFU